Uruguay vs Argentina Prediction 21.03.2025 | WC Qualifiers South America

• Competition: WC Qualifiers South America
• Date: Saturday, 21st, March 2025
• Kickoff: 23:30 UK / 00:30 CET
• Venue: Estadio Centenario (Montevideo)

The stage is set for a thrilling matchup between the two most impressive teams in the CONMEBOL World Cup qualifiers as Uruguay takes on Argentina at Estadio Centenario just after midnight on Saturday.

Uruguay kicks off the March qualifiers sitting comfortably in second place with a respectable haul of 20 points from 12 outings, and with a healthy seven-point gap ahead of Bolivia in the playoff hunt, they are inching closer to sealing their fifth straight automatic World Cup spot.

With six rounds remaining and a 12-point cushion over the seventh-placed side, Argentina stands on the brink of becoming the first South American nation to officially punch their ticket to the 2026 World Cup, provided they deliver the right results in their March qualifying doubleheader.

Uruguay vs Argentina Betting Tips : AH1 (0)

One of only three teams to hand Argentina a defeat in this qualification cycle is none other than Uruguay, who stunned the reigning World Cup champions with a clinical 2-0 win in the heart of Buenos Aires. Without their star player Lionel Messi, who picked up an injury just before the international gathering, it will be tough for La Albiceleste to seek revenge and solidify their position at the top, moreover, it wouldn't be surprising if the Uruguayans do a double over Scaloni's side. Among other things, it should not be overlooked that Los Charruas have not been easy to beat on their own territory, as they can proudly boast that they are one of just three teams to remain unbeaten in their six qualifying home matches, posting four wins and drawing two. In sharp contrast, Argentina have had a tough time on their recent away trips, with a 1-1 tie against Venezuela being their only point they earned from their last three qualification away games, while they fell to identical 1-2 losses to Colombia and Paraguay sandwiched between that draw. Given their challenges on the road and the absence of their iconic leader Messi, Argentina faces an uphill battle in breaching Uruguay’s unblemished home record, while the hosts seem determined to capitalize on this opportunity and move within touching distance of the top spot.